Force-dependent mechanical unfolding pathways of GFP
نویسندگان
چکیده
منابع مشابه
Force-dependent mechanical unfolding pathways of GFP
We characterize the force-dependent unfolding pathways and intermediate configurations of the green fluorescence protein (GFP) using novel atomistic simulations based on potential energy surface exploration. By using this approach, we are able to unfold GFP to significantly longer end-to-end distances, i.e. 40 nm, as compared to that seen in previous atomistic simulation studies. We find that t...
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ژورنال
عنوان ژورنال: Extreme Mechanics Letters
سال: 2016
ISSN: 2352-4316
DOI: 10.1016/j.eml.2015.12.001